Cardiology in New Hampshire

Design Standards Corporation is a vertically integrated medical device manufacturer with over 50 years of experience designing and manufacturing disposable and reusable medical devices for leading companies in healthcare. The company specializes in cardiothoracic devices and robotic surgical instruments, leveraging in-house capabilities spanning product design, CAD/Solidworks modeling, injection molding, tooling, and regulatory compliance (ISO 13485:2016). Services include end-to-end product development from concept through production, prototype testing, and manufacturing automation. Core competencies include medical device R&D, product design and development, regulatory assistance, and custom manufacturing of complex surgical instruments and cardiothoracic components.

Bearpac Medical manufactures the Passio™ Pump Drainage System, a digital handheld drainage device designed for patients with malignant pleural effusions (MPE). The Passio system represents a novel approach to pleural fluid management, enabling patients to manage their therapy with greater autonomy and comfort in outpatient or home settings. The company offers the Passio Pump as a complete system including a handheld control unit and a proprietary Pleural Catheter Insertion Kit. The device addresses a significant clinical need in oncology and pulmonology by providing convenient, controlled drainage for patients with fluid accumulation in the pleural space—a common complication in advanced malignancy. Bearpac positions the Passio as the first digital handheld system in this category, emphasizing patient comfort, control, and convenience. The company serves hospitals, outpatient facilities, and home care settings treating oncology patients with pleural complications. Product documentation and patient support materials are available in both English and Spanish, indicating attention to diverse patient populations.

1st Line Medical Inc. is a US-based sleep medicine and obstructive sleep apnea (OSA) solutions provider headquartered in Holderness, NH. The company manufactures and distributes FDA-cleared home sleep testing systems and oral appliance therapy devices designed to simplify and accelerate OSA diagnosis and treatment. Primary product lines include the SleepImage NightOwl home sleep testing system (wearable ring-based diagnostic) and SomnoGuard custom oral appliances (AP2 and SPX models), which represent alternatives to CPAP therapy for OSA and snoring management. The company also distributes Airlift hyoid suspension information for surgical candidates. 1st Line Medical serves airway specialist physicians, sleep medicine practitioners, and patients across the United States through a direct-to-provider and patient-facing model. The organization emphasizes rapid diagnostic pathways and treatment initiation, positioning products as time- and cost-effective solutions compared to traditional multi-month OSA diagnostic and therapeutic workflows. Products are FDA cleared for home use and carry regulatory approval for both diagnostic and therapeutic applications. The company provides physician training through the SomnoGuard Academy, practice support tools, prescription programs, and dedicated customer service (9 AM–5 PM EST, Monday–Friday). Distribution includes direct reordering of devices and supplies through their web portal.

DoseOptics manufactures BeamSite, an FDA-cleared Cherenkov imaging system that captures real-time video visualization of radiation therapy dose delivery to patients during treatment. BeamSite is the first clinical system to provide direct visual verification of radiotherapy beam placement and dose delivery by imaging Cherenkov light emissions. The company offers two product lines: BeamSite for clinical use in radiation oncology departments, and BeamSite Research for laboratory and research applications. By enabling clinicians to visually verify radiation therapy in real time, BeamSite supports treatment quality assurance, reduces delivery errors, and enhances patient safety. Clinical evidence demonstrates that visualization can identify suboptimal treatments that would otherwise go undetected. DoseOptics also partners with Vision RT to offer DoseRT, a Cherenkov imaging system integrated with Surface-Guided Radiation Therapy (SGRT) technology. The company serves radiation oncologists, medical physicists, radiation therapists, hospital administrators, and research institutions.