Clinical Laboratory in Pennsylvania

Menarini Silicon Biosystems is a clinical laboratory and diagnostic services company specializing in non-invasive biomarker detection and cell-based assays for oncology and precision medicine applications. The company is part of the Menarini Group and operates as a CLIA-certified laboratory offering proprietary circulating tumor cell (CTC) detection platforms and phenotyping services. Primary product is CELLSEARCH®, the first and only FDA-cleared actionable test for detecting and enumerating circulating tumor cells in patients with metastatic breast, prostate, and colorectal cancer, with clinical utility demonstrated in guiding therapeutic strategy and monitoring disease progression. The company also offers CELLSEARCH® Circulating Multiple Myeloma Cell Test for minimally invasive serological monitoring via blood draw, and emerging cell-based non-invasive prenatal testing (NIPT) technology for detection of fetal genomic abnormalities. Services include biomarker phenotyping, clinical laboratory testing for biopharma clinical trials, and comprehensive research support. The company serves oncology centers, biopharma sponsors, and healthcare systems requiring standardized, reliable CTC enumeration and biomarker profiling for patient stratification, treatment monitoring, and drug development. Quality and regulatory compliance are core operational principles.

Excelitas Technologies Corp. is a global leader in photonics, specializing in high-performance sensing, detection, and imaging solutions for biomedical, semiconductor, aerospace, and defense markets. Headquartered in Pittsburgh, PA, the company provides an extensive portfolio of photonic products including lasers, light sources, photodiodes, optical components, and integrated custom solutions. With heritage dating to the late 1800s and established as a PerkinElmer spinout in 2010, Excelitas delivers innovations spanning X-Cite fluorescence illuminators for medical diagnostics, thermal infrared sensors for thermal imaging, UV-LED curing systems for medical device manufacturing, Cermax xenon lamps, and precision optical assemblies. The company serves customers from concept through production, supporting applications in surgical visualization, laboratory automation, industrial inspection, and medical device assembly.

Meril Life Sciences is a global medical device manufacturer headquartered in Vapi, Gujarat, India, and founded in 2006. The company designs and manufactures innovative medical devices across multiple therapeutic specialties including cardiovascular interventions, orthopedic implants, minimally invasive endoscopic surgery tools, surgical robotics, and diagnostics. Meril operates as a multinational enterprise with 100% subsidiaries and regional headquarters spanning North America, Europe, Asia, Africa, and Australia. The company maintains a dedicated research and development function collaborating with surgeons and medical experts worldwide to address unmet clinical needs. Meril's product portfolio includes transcatheter heart valve systems (Myval THV and variants), orthopedic solutions through its Maxx Orthopedics division, endoscopic and minimally invasive surgical instruments, and robotic surgical platforms. The organization emphasizes clinical evidence generation and professional education through Meril Academy, a global platform offering fellowship programs and knowledge-sharing initiatives for healthcare professionals. Manufacturing and distribution capabilities span multiple continents, with established compliance and regulatory frameworks for markets including the United States, European Union, and Asia-Pacific regions. The company serves hospital systems, surgical centers, and healthcare institutions globally, with particular focus on advancing surgical interventions in cancer care and cardiovascular disease management.

Hausser Scientific Company manufactures laboratory glassware and counting equipment for clinical and research applications, with a primary focus on hemacytometers for cell counting. The company produces hemacytometers used for accurately counting red blood cells, white blood cells, platelets, and specimens in spinal and other body fluids. In addition to hemacytometers, Hausser Scientific offers custom-cut glass work based on customer specifications. Products are manufactured according to international standards and have established a worldwide reputation for reliability in laboratory and hospital settings. The company operates a manufacturing facility in Horsham, Pennsylvania and distributes products globally through laboratory and medical suppliers. Hausser Scientific serves the clinical laboratory, pathology, and research communities with counting and analytical equipment for hematology and body fluid analysis.

cyberDERM, inc. is a specialized manufacturer of noninvasive biomedical instrumentation and imaging systems for objective skin measurement and analysis. The company develops and refines innovative bio-instrumental and photographic methods for assessing skin structure, function, and the effects of topical treatments. They serve dermatology, cosmetics, pharmaceutical, and clinical research markets with a focus on clinical claim substantiation and instrument development. Product lines include ultrasound-based skin analysis systems (DermaScan C at 20 MHz and 50 MHz), colorimetry devices (Skin Colorimeter DSM-4), and comprehensive skin parameter measurement platforms (DermaLab Single and DermaLab Combo) that measure hydration, elasticity, TEWL (transepidermal water loss), subcutaneous structure, skin color, temperature, pH, sebum levels, and videomicroscopy. The company maintains a Technical Center in Broomall, PA for equipment service and calibration. cyberDERM has built an international reputation for cost-effective, innovative instrumentation meeting the specific needs of contract research organizations, cosmetic companies, pharmaceutical firms, and academic institutions conducting skin efficacy studies and product development.

Proscia, Inc. is an enterprise digital pathology and AI software platform company serving diagnostic laboratories, academic medical centers, health systems, pharmaceutical companies, contract research organizations (CROs), and biotech firms. The company develops and markets Concentriq, a purpose-built digital pathology platform offered in three modules: Concentriq LS for life sciences R&D and biomarker discovery; Concentriq AP for clinical laboratory digitization and workflow management; and Concentriq AP-Dx, which is FDA-cleared for primary diagnosis and supports both late-stage clinical trials and routine diagnostic operations. Proscia Aperture is a precision medicine analytics solution that converts pathology data into real-time, point-of-diagnosis patient insights for drug development and real-world evidence generation. The platform integrates AI analysis tools for pathologists and scientists, enabling automated image analysis, data harmonization across siloed sources, and collaborative research workflows. The company serves over 12,000 daily users across major diagnostic reference labs, 16 of the top 20 pharmaceutical companies, and leading academic institutions including Cleveland Clinic and PathGroup. Proscia holds FDA clearance for diagnostic applications and is recognized by KLAS as a leader in digital pathology. The company has raised significant capital to advance AI-driven pathology solutions and has been acknowledged by Fast Company and Fierce Biotech for innovation in AI and digital health.

Salimetrics is a research-focused bioanalytical laboratory specializing in salivary biomarker testing and analysis. Founded in 1998, the company has established itself as a leading provider of salivary bioscience services, with assays used in more published saliva-related research papers than any competitor in the field. The company offers comprehensive services including the Salimetrics CoreLab+, a central laboratory facility providing biomarker analysis from saliva and dried blood spot specimens. Core offerings include measurement of salivary hormones (cortisol, oxytocin, testosterone, DHEA-S, estradiol), inflammatory markers (CRP), and other signaling molecules relevant to biobehavioral research. Salimetrics also provides collection supplies, participant sampling packs, assay kits, and research study management tools designed to standardize sample collection and improve data quality. The company serves academic researchers, faculty, postdoctoral fellows, and principal investigators conducting biobehavioral studies across psychology, neuroscience, endocrinology, and related disciplines. Services include sample testing, assay kit provision, research consultation, and educational programs such as the Salivary Bioscience Bootcamp. The company emphasizes standardized protocols and maintains expertise in pre-analytical variables affecting sample integrity. Salimetrics operates a CLIA-certified laboratory and adheres to research-grade quality standards.

Plexision develops cellular biomarkers and diagnostic platforms for personalized medicine in solid organ transplantation and immunological disorders. The company specializes in biomarker discovery and validation, offering diagnostic services and R&D support across transplant rejection, viral infections, COVID-19, immune deficiency, and immuno-oncology applications. Plexision's technology platform enables risk assessment for immunological disorders, drug efficacy prediction for patient populations, and dosing optimization for new immunological therapeutics. The company operates a CLIA-certified laboratory in Pittsburgh, PA, supporting both clinical diagnostics and pharmaceutical drug development across preclinical through post-marketing phases. Services include biomarker integration into drug development pipelines and personalized diagnostic testing.

Röchling Medical Lancaster is a vertically integrated contract manufacturer for the medical device and pharmaceutical industries, operating since 1997 from Lancaster, PA. The company specializes in precision plastic and metal processing (including titanium), serving device manufacturers across orthopedics (spinal implants, bone pastes), endoscopy (flexible and rigid hand-held devices), ophthalmology (eye surgery devices), general surgery, diabetic delivery systems, drug delivery systems (pen injectors), diagnostics (in vitro and point-of-care), cardiovascular, dental, and bio-defense applications. Notable product expertise includes sterile bifurcated needles for smallpox/mpox vaccination and allergy testing. Manufacturing capabilities include 14 injection molding machines (20–180 ton capacity), insert molding, micromolding, metal processing, complex device assembly, and contract packaging. The facility operates ISO 14644-1 Class 7 and Class 8 certified cleanrooms compliant with Pharma GMP Class C standards. The company offers end-to-end services: product design and development, tool making and maintenance, automation engineering, assembly and post-processing, packaging development, and sterilization coordination. Röchling Medical Lancaster holds ISO 13485 certification (Medical Devices Quality Management Systems) and is FDA registered. The parent Röchling Group is a global leader in engineered plastics and composites. The company maintains regulatory expertise in Medical Device Regulation (MDR) and compliance with relevant healthcare standards. As a B2B supplier, it serves OEMs requiring cost-effective, scalable manufacturing with simplified supply chains and quality assurance tailored to product-specific regulatory requirements.