Semler Scientific, Inc.

Semler Scientific is a medical technology company specializing in early detection and management of vascular diseases, particularly peripheral arterial disease (PAD). Founded in 2007, the company develops point-of-care diagnostic devices and digital health platforms for cardiovascular assessment. QuantaFlo, its flagship product, is an FDA-cleared non-invasive test measuring arterial blood flow in extremities, enabling rapid diagnosis of PAD in both symptomatic and asymptomatic patients. The company also provides complementary solutions including SemlerShield (data security), SemlerVault (data management), SemlerAnalytics (clinical analytics), SemlerSimulation (provider training), and SemlerHub (cloud-based diagnostic platform). Semler Scientific serves healthcare providers seeking portable, evidence-based tools for vascular disease screening and monitoring, addressing the significant clinical and economic burden of PAD, which affects approximately 1 in 5 people over age 60 and costs the U.S. healthcare system over $216 billion annually.