SPR Therapeutics, Inc

SPR Therapeutics is a Cleveland-based medical device company specializing in peripheral nerve stimulation (PNS) technology for non-opioid, non-surgical pain management. Founded in 2010, the company develops innovative neuromodulation solutions targeting chronic pain, acute pain, post-surgical pain, and post-traumatic pain. The company's flagship product, the SPR® SPRINT® Peripheral Nerve Stimulation System, is the only FDA-approved percutaneous PNS system designed for both chronic and acute indications. SPR Therapeutics' mission centers on providing drug-free alternatives to opioids and invasive surgical procedures, directly addressing the opioid crisis. The company has demonstrated strong clinical evidence with over 200 patents, Department of Defense and NIH funding support, and real-world efficacy showing pain relief in over 70% of patients with more than 50,000 implants performed. SPR continues to advance next-generation pain therapies while expanding market coverage and clinical adoption.