Sylke, Inc.

SYLKE, Inc. is a medical technology company specializing in innovative wound closure and wound care solutions using silk fibroin-based adhesives. Founded in 2023 by Dr. M. Mark Mofid, a plastic and reconstructive surgeon, SYLKE develops sterile, single-use silk fibroin mesh strips with medical-grade pressure-sensitive adhesives for surgical incision management. The flagship product, SYLKE® Adhesive Wound Closure, provides a breathable, biocompatible barrier that secures wound edges for up to 14 days without requiring drying time. Available in three sizes (16cm, 24cm, 32cm) with flexible box quantities, the product is water-resistant and designed for both clinical and home settings. SYLKE has established presence in over 100 U.S. hospital systems including Cleveland Clinic, Johns Hopkins, UC Health, and Northwell Health. The company has received industry recognition including the 2025 AAHKS Industry Innovation Award and Breakthrough Designation with Premier GPO. Beyond the core wound closure line, SYLKE markets antimicrobial silk apparel products.