Zetroz Systems

ZetrOZ Systems is a FDA-cleared medical device manufacturer specializing in wearable bioelectronic devices for sustained acoustic medicine (SAM®). Based in Trumbull, Connecticut and founded in 2008, the company develops non-invasive, battery-powered ultrasound therapy systems designed to accelerate tissue healing and manage pain in chronic musculoskeletal conditions. Their proprietary OZ Inside™ technology enables miniaturized, flexible ultrasound delivery for extended treatment sessions. The SAM® product line treats conditions including knee osteoarthritis, chronic back pain, and tendon injuries through low-intensity, long-duration ultrasound proven to promote healing rather than symptom relief alone. ZetrOZ holds 46 patents and manufactures all products in the USA across four domestic facilities. The company collaborates with federal agencies (NIH, NASA, DOD), sports medicine organizations (USA Field Hockey, National Basketball Trainers Association), and healthcare providers. Devices are used in clinical settings and target sports medicine, orthopedic recovery, and workers' compensation applications.