AI & Diagnostics Software in North Carolina

623 Medical is a medical technology company specializing in nüm®, a sterile, single-patient-use topical anesthetic spray designed to reduce pain and anxiety associated with needle-related procedures. The fast-acting vapocoolant spray provides rapid numbing to the skin prior to vaccinations, blood draws, IV starts, injections, port access, biopsies, and minor surgical procedures. nüm eliminates cross-contamination risk through single-patient use and sterility assurance, while offering immediate onset without messy creams or loud devices. The product is particularly valuable for pediatric patients and adults with injection phobias, improving procedural comfort and patient satisfaction across healthcare settings.

Leica Microsystems, a Danaher company, manufactures and sells optical and digital microscopy solutions for life science research, medical/surgical applications, industrial inspection, forensics, and education. The company serves over 175 years of heritage in revealing microscopic structures through advanced imaging technology. Product portfolio includes light microscopes (inverted and stereo), surgical microscopes for ophthalmology, neurosurgery, ENT, plastic reconstructive surgery, and dentistry. Key products include the DMi8 inverted microscope platform for research workflows, MyVeo all-in-one surgical visualization headset for heads-up OR collaboration, Ivesta 3 Greenough stereo microscopes for industrial inspection, Stellaris confocal microscopes, and Proveo 8x 3D digital surgical microscopes. The company offers sample preparation equipment including the UC Enuity ultramicrotome for electron microscopy. Aivia is their AI-powered 2-to-5D image visualization, analysis, and interpretation platform for complex image processing. ATTO-TEC consumables (fluorescent dyes) serve fluorescence microscopy imaging applications. Leica operates an online shop with pre-configured bundles and provides remote care/predictive service systems. The company maintains global distribution through authorized partners and serves clinical, research, and industrial markets. Regional presence includes Germany (headquarters in Wetzlar) with US operations.

Hydromer, Inc. is a global B2B provider of surface modification and coating solutions, specializing in hydrophilic polymer research, development, and manufacturing. Founded in 1980 and based in Concord, North Carolina, the company is ISO 9001:2015 certified with over 40 years of expertise in creating innovative polymer-based products for medical devices, industrial plastics, and specialized applications. Hydromer offers a comprehensive portfolio of hydrophilic coatings—including UV-curable and thermal-curable systems—tailored for cardiovascular, gastroenterology, neurovascular, ophthalmology, peripheral vascular, and urological devices. The company provides end-to-end services including custom formulation development, contract coating, R&D services, FDA regulatory support, and technology transfer. With a 98% repeat customer rate and support for over 1,000 medical device customers worldwide, Hydromer delivers lubricious, anti-thrombogenic, and performance-enhanced coatings for catheters, guidewires, balloons, stents, endoscopes, and other interventional and diagnostic devices. Global production and service hubs ensure consistent quality and responsive support across Asia and the Americas.